Survey of influenza antibody in England by the strain-specific complement-fixation test.

The first recorded case of recovery from hepatic coma after an exchange blood transfusion was that of Lee and Tink (1958). They gave two exchange transfusions of fresh blood to a boy aged 13 who was deeply jaundiced and comatose. After the first transfusion of 3,260 ml. his condition was unchanged, but when a second exchange of 3,140 ml. was given he improved and recovered completely. Trey et al. (1965) reported seven cases treated by exchange transfusion. Approximately twice the patient's blood volume was exchanged. Freshly donated heparinized blood was administered under pressure on the venous side while blood was simultaneously removed from an artery. Five of the seven cases recovered completely. They were fully reported by Trcy et al. (1966). Berger et al. (1966) put on record another recovery from fulminating hepatitis after exchange transfusion. In the above cases fresh heparinized blood was used, and it is the purpose of this paper to describe a technique for directly giving large quantities of unmodified blood.